How is FUZEON® different from other HIV treatments?
Like other viruses, HIV makes new copies of itself (or replicates) inside the cells it infects. Combination therapy with HIV drugs stops HIV from making copies of itself at different stages of the replication cycle.
There are currently 6 classes of HIV drugs. Nucleoside reverse transcriptase inhibitors (NRTI), non-nucleoside reverse transcriptase inhibitors (NNRTI), and protease inhibitors (PI) work inside the CD4 cell to keep HIV from replicating once it has entered the cell. Integrase inhibitors (INIs) block the activity of the integrase enzyme to prevent HIV DNA from meshing with healthy cell DNA. FUZEON is the only fusion inhibitor (FI) and it works outside the T cell to block HIV from entering it. CCR5 inhibitors (CIs) block HIV by binding to the CCR5 coreceptor before the virus does.
Learn more at How does FUZEON Work?.