4. Mixing FUZEON
Draw Up Sterile Water
- Gently tap the FUZEON vial to loosen the powder
- Pick up the 3-cc/mL (large) syringe
- Using your index finger, pull the colored protection device away from the capped needle
- To ensure that the needle is secure, hold the clear plastic cap and tighten the needle with a gentle clockwise twist. Do not use too much force as the needle may loosen
- Pull the clear plastic cap off
- Pull the plunger back to get 1.1 cc/mL of air [4A]
- Before turning the sterile water vial upside down, slowly inject the air into the vial — and keep the needle in the vial
- Turn the vial upside down. Make sure the tip of the needle is always below the surface of the water to help keep air bubbles from entering the syringe [4B]
- Slowly pull the plunger back to get 1.1 cc/mL of sterile water into the syringe
Tip! Gently tap or flick the barrel and push and pull the plunger to remove extra air and bubbles. To be sure you end up with 1.1 cc/mL of sterile water in the syringe, you may need to pull the plunger past the 1.1 cc/mL mark. [4C]
- Carefully remove the needle and syringe from the vial
Inject Sterile Water Into FUZEON
- Insert the syringe with sterile water into the FUZEON vial at an angle
- Inject the sterile water slowly, so that it drips down the side of the vial into the FUZEON powder [4D]
- Remove the needle from the vial. Using one hand, gently press the colored protective cover against a flat surface until you hear a click and the needle is re-covered. Never use your hand to re-cover the needle
- Put the used syringe in the sharps container [4E]
Gently Mix FUZEON
- Gently tap the FUZEON vial with your fingertip for 10 seconds to start dissolving the powder. Then gently roll the FUZEON vial between your hands to reduce the mixing time. [4F] Make sure no FUZEON is stuck to the vial wall. After tapping, it could take up to 45 minutes to dissolve
Important! Never shake the FUZEON vial. Shaking will make the medicine foam and it will take much longer to dissolve.
- Once the powder starts to dissolve, just set it aside and it will completely dissolve
Inspect FUZEON
- When completely mixed, the liquid FUZEON should be clear
Important! Completely dissolved FUZEON should be clear and without foam. [4G] If the FUZEON is foamy, allow more time for it to dissolve. [4H]
- If you see bubbles, gently tap the vial until they disappear
- If you see any particles in the FUZEON once it is completely mixed, do not use that vial. Contact the pharmacy that provided it
- Mixed FUZEON must be used right away or stored in the vial in the refrigerator and used within 24 hours. Do not store mixed FUZEON in the syringe
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